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2025 NFL Playoffs – Wildcard Preview: Our Expert Tips

January 10, 2026

2025 NFL Playoffs – Wildcard Preview: Our Expert Tips

The regular season is done and the NFL Playoffs are upon us. The real games start now and we will have a preview of every single game from now until the Super Bowl.

I will likely be adding some more picks before the games, so make sure to check


Los Angeles Rams @ Carolina Panthers

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This NFC Wild Card matchup looks lopsided on paper — the Rams enter as big favourites — but the Panthers +10.5 offers strong ATS appeal given current news and roster conditions. Carolina clinched a playoff berth as NFC South champions and is playing its first home postseason game in nearly a decade, energizing a fan base that can influence field position and momentum in a hostile playoff atmosphere. They already beat the Rams earlier this season as significant underdogs, showing they can disrupt Los Angeles’ game plan on both sides of the ball. Carolina’s roster is largely healthy, with key players like defensive tackle Derrick Brown and safety Nick Scott available, and springing onside or fourth-down surprise plays is well within their identity.

Los Angeles brings star power — including the expected return of Davante Adams — but they’re not without setbacks. The Rams will be missing guard Kevin Dotson (ankle) and WR Jordan Whittington (knee), with additional contributors like TE Terrance Ferguson and CB Josh Wallace listed as questionable. That impacts protection and depth in passing situations, reducing their offensive ceiling. Meanwhile, Carolina’s coaching staff has shown tactical aggressiveness and willingness to convert on fourth down and in pressure moments — a trend that becomes more critical in the postseason.

In playoff spreads of this size, “double-digit underdogs” at home who have previously beaten the favorite are historically more competitive ATS than the public expects. If Carolina controls tempo and forces mistakes from a somewhat banged-up Rams unit, they should keep this within reach — and cover the +10.5.

Pick: Panthers +10.5

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Green Bay Packers @ Chicago Bears

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This NFC Wild Card matchup between the Packers and Bears feels as even as any rivalry game can get, but there’s clear value backing the Chicago Bears to win outright in their home playoff opener. Chicago secured the No. 2 seed in the NFC after capturing the division, and they’ve already split the season series with Green Bay — each team earning a close victory in Soldier Field and Lambeau Field. Chicago’s balance on both sides of the ball gives them a path to pull this off.

Recent injury news has also tilted slightly in the Bears’ favour. Star wide receiver Rome Odunze is expected to return after missing time with a foot injury, and he practiced fully this week, adding a dynamic vertical element to Chicago’s offense. At the same time, they will be without slot corner C.J. Gardner-Johnson and linebacker Amen Ogbongbemiga, but corner Kyler Gordon and tackle Ozzy Trapilo practiced and look likely to be activated — stabilizing key units.

Green Bay is dealing with its own availability questions. Multiple Packers — including QB Malik Willis (shoulder/hamstring), safety Javon Bullard, and tackle Zach Tom — are all listed as questionable for this game, making offensive continuity uncertain. Meanwhile, utility player Bo Melton will miss the playoffs after being placed on IR, weakening depth in receiving and defensive roles.

Trend-wise, rivalry playoff games often boil down to turnovers and third-down efficiency — areas where the Bears have excelled at home. With Odunze back and a more balanced attack, Chicago has the structure and motivation to win this rivalry playoff game outright.

Pick: Bears ML (win outright)

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Buffalo Bills @ Jacksonville Jaguars

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This AFC Wild Card clash between the Bills and Jaguars sets up as a ripe spot to back Buffalo to win outright despite the road setting. The Bills enter the postseason with high expectations and a balanced attack led by Josh Allen, who has produced elite dual-threat numbers throughout the season and will look to dictate tempo early. Allen’s ability to extend plays and run when needed gives Buffalo an edge in two-minute and third-down situations that often decide playoff games.

Recent injury news clouded portions of the Bills’ roster, but the team still has enough impact players to tilt the matchup. Buffalo ruled out linebacker Terrel Bernard, cornerback Maxwell Hairston, and safety Damar Hamlin for this game, creating depth questions in the secondary and linebacker corps. At the same time, Buffalo added veteran cornerback Dane Jackson to shore up back-end depth, and key pieces such as Joey Bosa (hamstring) and Cole Bishop are available to help generate pressure and turnovers.

Offensively, Buffalo’s strength remains its run-pass balance, with James Cook’s ground productivity forcing defenders to respect pace while Dalton Kincaid and Dawson Knox provide matchup problems over the middle when healthy. Jacksonville’s defense is stout overall, but Buffalo’s ability to capably mix plays and control key situations late makes the Bills the more complete playoff team. Their road success and postseason experience further elevate confidence here.

Pick: Bills ML (win outright)

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San Francisco 49ers @ Philadelphia Eagles

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The Wild Card round delivers a heavyweight NFC clash as the San Francisco 49ers travel east to face the Philadelphia Eagles, and the matchup lines up well for the home side to cover −5.5. Philadelphia enters the postseason healthier than it’s been in weeks, with key offensive pieces active and the offense trending upward behind a balanced, physical approach. Their ability to control tempo with the run while still creating explosive plays through the air gives them flexibility against a disciplined San Francisco defense.

The 49ers arrive off a taxing end to the regular season and carry some question marks into the Wild Card round, particularly around skill-position health and depth in the secondary. Any limitations there could be costly against an Eagles offense that stresses defenses horizontally and vertically. Philadelphia’s defensive front is also well-suited for playoff football, capable of collapsing the pocket without heavy blitzing and forcing long, mistake-prone drives.

From an ATS standpoint, home favorites in the 5–6 point range during Wild Card weekend historically perform well, especially when they own the trenches and have continuity at quarterback. With home-field energy, cleaner injury status, and a playoff-tested roster, Philadelphia is positioned to create separation in the second half and cover the number.

Pick: Eagles −5.5

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Los Angeles Chargers @ New England Patriots

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This Wild Card matchup sees the Patriots favored by −3.5 at home, and the betting edge tilts toward New England to cover due to recent roster developments and matchup advantages. The Patriots enter the postseason healthier and more consistent than they’ve been in recent weeks. Drake Maye is trending as an MVP candidate, showcasing poise, accuracy, and leadership down the stretch, and his connection with top targets remains strong. Maye’s ability to create in tight spaces and sustain drives adds a layer of offensive balance that neutralizes pressure packages.

New England’s defense also enters relatively intact, with only a handful of role players listed as questionable, while key contributors on the frontline and in the secondary are available. That depth will be crucial against a Chargers offense that has shown flashes but remains inconsistent in critical moments.

Los Angeles travels with its own injury questions. The Chargers have listed multiple skill-position players and defensive contributors as questionable or limited late in the week, creating uncertainty around their ability to close out drives and generate timely stops. Their offensive line has been inconsistent protecting Justin Herbert, and lingering questions about pass protection could prove costly against a Patriots front that excels at situational pressure.

From an ATS perspective, home playoff favorites of less than a touchdown who can control tempo and win third-down situations cover at a higher clip, especially when the road team enters with health questions. If New England controls the clock with an effective run/pass mix and keeps the Chargers off rhythm, they should cover this number comfortably.

Pick: Patriots −3.5

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Houston Texans @ Pittsburgh Steelers

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This AFC Wild Card matchup sets up as a classic playoff grinder, and there’s solid value on the Steelers +3 at home. Pittsburgh enters the postseason battle-tested, leaning into its identity of physical defense, situational football, and capitalising on mistakes. The Steelers’ defense has been trending in the right direction over the past week, with key contributors available up front, giving them the ability to pressure quarterbacks without excessive blitzing—an important factor against a young Texans offense.

Houston arrives with momentum but also some uncertainty. The Texans have dealt with late-week injury management across the roster, particularly in the skill positions and secondary, which could limit their flexibility if forced into a tight, low-scoring game. While C.J. Stroud has been impressive, this is his first road playoff environment, and Pittsburgh remains one of the league’s most difficult venues when the stakes are highest.

Offensively, the Steelers may not need fireworks to stay competitive. A controlled game plan, emphasis on field position, and patience in the red zone fits the playoff script. Historically, home underdogs of a field goal or less in the Wild Card round tend to outperform the number, especially when they can shorten the game and lean on defense.

If Pittsburgh keeps Houston out of rhythm early and forces long drives, this matchup should remain within one score throughout.

Pick: Steelers +3

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