NFL Weekly Preview Week 1 2025: Key Injuries, Difference Makers & Projected Upsets
September 5, 2025
Jayden Daniels (YouTube)
We begin the 2025 NFL regular season on Thursday. Here are the key injuries, fantasy stars and projected upsets.
Key Injuries
Houston Texans running back Joe Mixon of Oakley, California is dealing with a foot/ankle problem, and will be out long term. To replace Mixon, the Texans have signed Nick Chubb of Cedartown, Georgia to a one-year deal worth $2.5 million. Chubb was with the Cleveland Browns the last seven years.
The New Orleans Saints will be without their two top tight ends to start the year. Taysom Hill of Pocatello, Idaho is recovering from a torn anterior cruciate ligament from the end of last season, and Foster Moreau of New Orleans, Louisiana is out with a knee injury. Meanwhile, Dolphins kicker Jason Sanders is out with a hip injury.
Difference Makers
The top quarterback of the week is Jayden Daniels of the Washington Commanders. The native of San Bernardino, California is projected to have 223 yards passing, 53 yards and two touchdowns against the New York Giants on Sunday. The top wide receiver is CeeDee Lamb of the Dallas Cowboys. The native of Opelousas, Louisiana is projected to get nine catches for 97 receiving yards and one touchdown in the NFL season opener tonight in Philadelphia. The top running back is Saquon Barkley of The Bronx, New York. He is projected to get 105 yards rushing, 14 yards receiving and one touchdown tonight for the Eagles against the Cowboys.
Projected Upsets
I am projecting seven underdogs to win in Week One. They are the Miami Dolphins, Las Vegas Raiders, Seattle Seahawks, Houston Texans, Detroit Lions, Baltimore Ravens and Minnesota Vikings.
May 25, 2026
Black Book: Horses You Must Follow From Randwick 23/5
The replays and sectional times have been reviewed from the first meeting back at Randwick in a month on Saturday Our analyst has Black Booked as pair of place getters that look ready to hit the Read MoreMay 25, 2026
Moses in doubt for Origin opener after pulling up with hamstring tightness
New South Wales may have to bring in another five-eighth for Wednesday's State of Origin series opener, with Mitchell Moses heading for scans after pulling up sore with hamstring tightness after a Read MoreMay 24, 2026
Shibasaki now 'considering' leaving Broncos after $300K gap in expectations
Gehamat Shibasaki has said he's "considering" leaving the Brisbane Broncos at the end of the season after he asked for a $600,000 a year extension and was instead offered just $300K a year to play on Read More
Tell Us What You Think Below